The PICO format is often used to to help define and answer your research question.
By organizing a research question using PICO, a researcher can determine specific terms that will help find relevant evidence in professional literature
Questions addressing how a clinical issue, illness, or disability is treated.
"In__________________(P), how does__________________(I) compared to_________________(C) affect______________(O)?"
Etiology
Questions that address the causes or origin of disease, the factors which produce or predispose toward a certain disease or disorder.
"Are_________________(P), who have_________________(I) compared with those without_________________(C) at_________________risk for/of_________________(O) over_________________(T)?"
Diagnosis:
Questions addressing the act or process of identifying or determining the nature and cause of a disease or injury through evaluation.
In_________________(P) are/is_________________(I) compared with_________________(C) more accurate in diagnosing_________________(O)?
Prognosis/Prediction:
Questions addressing the prediction of the course of a disease.
In_________________(P), how does_________________(I) compared to_________________ (C) influence_________________(O)?
Meaning
Questions addressing how one experiences a phenomenon or why we need to approach practice differently.
"How do_________________(P) with_________________(I) perceive_________________(O)?"
Adapted from: Melnyk, B. M., & Fineout-Overholt, E. (2011). Evidence-based practice in nursing & healthcare: A guide to best practice. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.
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